- 1School of Biotechnology (KSBT), KIIT University 24, INDIA
- 2Regional Medical Research Center (ICMR), Bhubaneswar 23, INDIA
Can J Biotech, Volume 1, Special Issue, Page 127, DOI: https://doi.org/10.24870/cjb.2017-a113
Presenting author: email@example.com
Staphylococcus aureus is a major gram positive bacterial pathogen that causes a wide spectrum of clinical infections, ranging from localized soft-tissue infections to life-threatening bacteremia and endocarditis. S. aureus can infect tissues when the skin or mucosal barriers have been breached. This can lead to many different types of infections, including boils, carbuncles (a collection of boils) and abscesses. Deeply penetrating S. aureus infections can be severe. The incidence of methicillin resistant S. aureus (MRSA) in India ranges from 30-70%. The present study investigates the detection of S. aureus from pus swabs of hospitalized patients (Capital Hospital, Bhubaneswar) having skin infections and abscesses and its’ susceptibility pattern to different antibiotics. Out of 230 samples collected 204 (88.9%) were culture positive for different bacterial pathogens from which S. aureus was 54 (23%). The incidence rate of S. aureus among male and female group studied was 56.3% and 43.7%, respectively. The isolated S. aureus was found to be resistant to most of the antibiotics such as azithromycin, doxycycline, ciprofloxacin, tetracycline, gentamycin, ofloxacin, chloramphenicol, ampicillin and oxacillin. Among the various antibiotics, the isolated S. aureus strains revealed resistant to methicillin (MRSA) and vancomycin (VRSA) were 90.7% and 14.8, respectively. The MRSA strains were confirmed genotypically by amplification of methicillin resistant (mec A) gene. S. aureus identification and its antibiogram profile are highly essential for implementation of treatment and control of the infection in Odisha.